A classic, though with slightly fewer laughs than the Bible.
↓ Transcript
Panel 1:
Estragon and God
Estragon: God, while I've got you here, can I ask you a question?
Panel 2:
Estragon and God
God: Make it snappy. I've got to appear in a burrito in Honduras.
Panel 3:
Estragon and God
Estragon: What's the meaning of life?
God: It's 42, idiot. Were you not paying attention when I gave you the holy book?
Estragon and God
Estragon: God, while I've got you here, can I ask you a question?
Panel 2:
Estragon and God
God: Make it snappy. I've got to appear in a burrito in Honduras.
Panel 3:
Estragon and God
Estragon: What's the meaning of life?
God: It's 42, idiot. Were you not paying attention when I gave you the holy book?
Nice.
Win?